Cryogel that preserves bacteria without the need for refrigeration developed at Novosibirsk Technical University
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- Novosibirsk State Technical University has developed a biodegradable cryogel that can preserve bacteria at room temperature.
- The cryogel has the potential to replace traditional energy-consuming freezing storage and lyophilization methods.
- The material is designed to withstand stomach acid and deliver probiotics directly to the intestine.
- The technology is planned to be used in the medicine, food, biopharmaceutical, and agriculture sectors.
Researchers at Novosibirsk State Technical University (NSTU) have developed a biodegradable cryogel that enables microorganisms to survive even without expensive cold chain conditions. This new material allows bacteria to remain active for long periods, even at room temperature. The developed technology stands out as an alternative to energy-intensive traditional storage methods.
The cryogel has the potential to be used in many fields such as medicine, the food industry, biopharmaceuticals, and agriculture. The material can be used in the targeted delivery of drugs, the production of probiotics, and the storage of yogurt cultures. Additionally, it is planned to be evaluated for the preservation of collection strains and the creation of microbiological preparations for agriculture.
According to project manager Anastasia Korel, the cryogel works like a protective shield, protecting probiotics from the acidic environment in the stomach and gradually releasing the cells in the slightly alkaline environment of the intestine. Thanks to chitosan modification, the material's toxicity is reduced and made safe for intestinal cells, thus enabling it to deliver probiotics directly to the intestine.
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- What does the developed cryogel do?
- The cryogel enables microorganisms to stay alive for long periods even at room temperature without the need for expensive conditions like a cold chain or deep freezing.
- In which fields can this technology be used?
- It can be used in the storage and transportation of probiotics, drugs, and microbiological preparations, including medicine, the food industry, biopharmaceuticals, and agriculture.
- How does the cryogel deliver probiotics to the intestine?
- The cryogel maintains its structure in the acidic environment of the stomach and gradually dissolves when it reaches the slightly alkaline environment of the intestine, releasing the microorganisms there.
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