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Prolonged uninterrupted sitting increases cancer death risk by 9%

Kütahya Ekspres
Prolonged uninterrupted sitting increases cancer death risk by 9%
Photo: kutahyaekspres.com

Key Points

  • Each additional hour of uninterrupted sitting increases the risk of cancer death by 9%.
  • Breaking up sitting time with light movement reduces the risk by 12%.
  • An association was also found in obesity- and diabetes-related cancers using data from 91 thousand people over 12 years.
  • The study does not prove causality; results may not be generalizable to the general population.

By the Numbers

91,292 participants%9 risk increase per hour12.38 years median follow-up%12 risk reduction with light activity

A study published in the journal PLOS Medicine by researchers from the University of Glasgow examined the follow-up data of 91,292 participants over 12.38 years. It was determined that each additional hour of uninterrupted sitting increased the risk of cancer death by 9 percent.

The research showed that breaking up sitting time with short bouts of movement reduced the risk; replacing one hour of daily uninterrupted inactivity with light activity reduced the risk of cancer death by 12 percent. A similar association was found in cancers linked to obesity and type 2 diabetes.

Since the study was observational, causality could not be established, and it was noted that UK Biobank volunteers may be more active than the general population. The authors emphasized that current exercise recommendations need to be expanded to include light movement.

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Frequently Asked Questions

How is uninterrupted sitting defined?
Periods lasting at least 30 minutes during which the person remains immobile for at least 90% of that time.
Which cancer types were associated?
Esophageal, liver, kidney, pancreatic, colorectal, breast, ovarian, and thyroid cancers linked to obesity, as well as cancers linked to type 2 diabetes.
What is the study's biggest limitation?
The observational design cannot establish a cause-effect relationship, and participants may be healthier than the general population.

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